Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50305795
(((3aR,6aS)-5-(2-(1-(3,3-difluorocyclobutanecarbony...)Show SMILES Cc1nc(nc(C)c1C(=O)N1C[C@@H]2CN(CCC3(CN(C3)C(=O)C3CC(F)(F)C3)c3ccccc3)C[C@@H]2C1)C(F)(F)F |r| Show InChI InChI=1S/C30H34F5N5O2/c1-18-24(19(2)37-27(36-18)30(33,34)35)26(42)39-14-21-12-38(13-22(21)15-39)9-8-28(23-6-4-3-5-7-23)16-40(17-28)25(41)20-10-29(31,32)11-20/h3-7,20-22H,8-17H2,1-2H3/t21-,22+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR5 |
Bioorg Med Chem Lett 20: 704-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.072
BindingDB Entry DOI: 10.7270/Q22R3RSC |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50305795
(((3aR,6aS)-5-(2-(1-(3,3-difluorocyclobutanecarbony...)Show SMILES Cc1nc(nc(C)c1C(=O)N1C[C@@H]2CN(CCC3(CN(C3)C(=O)C3CC(F)(F)C3)c3ccccc3)C[C@@H]2C1)C(F)(F)F |r| Show InChI InChI=1S/C30H34F5N5O2/c1-18-24(19(2)37-27(36-18)30(33,34)35)26(42)39-14-21-12-38(13-22(21)15-39)9-8-28(23-6-4-3-5-7-23)16-40(17-28)25(41)20-10-29(31,32)11-20/h3-7,20-22H,8-17H2,1-2H3/t21-,22+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 168 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto
Curated by ChEMBL
| Assay Description
Antagonist activity at human recombinant CCR5 by cell-cell fusion assay |
Bioorg Med Chem Lett 20: 704-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.072
BindingDB Entry DOI: 10.7270/Q22R3RSC |
More data for this
Ligand-Target Pair | |