Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 600.7 BDBM50418506

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50418506 (CHEMBL1784482) Show SMILES Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(CCN(CC1)C(=O)c1ccc(cc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C36H39F3N4O/c1-25-40-32-9-5-6-10-33(32)43(25)31-23-29-15-16-30(24-31)42(29)22-19-35(27-7-3-2-4-8-27)17-20-41(21-18-35)34(44)26-11-13-28(14-12-26)36(37,38)39/h2-14,29-31H,15-24H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of 125I-MIP-1beta from human CCR5 receptor after 4 hrs by scintillation counting				J Med Chem 54: 3756-67 (2011) Article DOI: 10.1021/jm200279v BindingDB Entry DOI: 10.7270/Q26111K7
					More data for this Ligand-Target Pair