Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50305783
(1-(3-(2-((3aR,6aS)-5-(4,6-dimethylpyrimidine-5-car...)Show SMILES Cc1ncnc(C)c1C(=O)N1C[C@@H]2CN(CCC3(CCN(C3)C(=O)C(C)(C)C)c3ccccc3)C[C@@H]2C1 |r| Show InChI InChI=1S/C30H41N5O2/c1-21-26(22(2)32-20-31-21)27(36)35-17-23-15-33(16-24(23)18-35)13-11-30(25-9-7-6-8-10-25)12-14-34(19-30)28(37)29(3,4)5/h6-10,20,23-24H,11-19H2,1-5H3/t23-,24+,30? | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 242 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR5 |
Bioorg Med Chem Lett 20: 704-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.072
BindingDB Entry DOI: 10.7270/Q22R3RSC |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50305783
(1-(3-(2-((3aR,6aS)-5-(4,6-dimethylpyrimidine-5-car...)Show SMILES Cc1ncnc(C)c1C(=O)N1C[C@@H]2CN(CCC3(CCN(C3)C(=O)C(C)(C)C)c3ccccc3)C[C@@H]2C1 |r| Show InChI InChI=1S/C30H41N5O2/c1-21-26(22(2)32-20-31-21)27(36)35-17-23-15-33(16-24(23)18-35)13-11-30(25-9-7-6-8-10-25)12-14-34(19-30)28(37)29(3,4)5/h6-10,20,23-24H,11-19H2,1-5H3/t23-,24+,30? | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto
Curated by ChEMBL
| Assay Description
Antagonist activity at human recombinant CCR5 by cell-cell fusion assay |
Bioorg Med Chem Lett 20: 704-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.072
BindingDB Entry DOI: 10.7270/Q22R3RSC |
More data for this
Ligand-Target Pair | |