Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50305789
(1-(3-(2-((3aR,6aS)-5-(4,6-dimethylpyrimidine-5-car...)Show SMILES Cc1ncnc(C)c1C(=O)N1C[C@@H]2CN(CCC3(CN(C3)C(=O)C(C)(C)CO)c3ccccc3)C[C@@H]2C1 |r| Show InChI InChI=1S/C29H39N5O3/c1-20-25(21(2)31-19-30-20)26(36)33-14-22-12-32(13-23(22)15-33)11-10-29(24-8-6-5-7-9-24)16-34(17-29)27(37)28(3,4)18-35/h5-9,19,22-23,35H,10-18H2,1-4H3/t22-,23+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR5 |
Bioorg Med Chem Lett 20: 704-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.072
BindingDB Entry DOI: 10.7270/Q22R3RSC |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50305789
(1-(3-(2-((3aR,6aS)-5-(4,6-dimethylpyrimidine-5-car...)Show SMILES Cc1ncnc(C)c1C(=O)N1C[C@@H]2CN(CCC3(CN(C3)C(=O)C(C)(C)CO)c3ccccc3)C[C@@H]2C1 |r| Show InChI InChI=1S/C29H39N5O3/c1-20-25(21(2)31-19-30-20)26(36)33-14-22-12-32(13-23(22)15-33)11-10-29(24-8-6-5-7-9-24)16-34(17-29)27(37)28(3,4)18-35/h5-9,19,22-23,35H,10-18H2,1-4H3/t22-,23+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto
Curated by ChEMBL
| Assay Description
Antagonist activity at human recombinant CCR5 by cell-cell fusion assay |
Bioorg Med Chem Lett 20: 704-8 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.072
BindingDB Entry DOI: 10.7270/Q22R3RSC |
More data for this
Ligand-Target Pair | |