Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50141863
((R)-2-((3S,4S)-3-((4-(3-benzyl-1-methyl-1H-pyrazol...)Show SMILES Cn1nc(Cc2ccccc2)cc1C1CCN(C[C@H]2CN(C[C@@H]2c2ccccc2)[C@H](C2CCCCC2)C(O)=O)CC1 |r| Show InChI InChI=1S/C35H46N4O2/c1-37-33(22-31(36-37)21-26-11-5-2-6-12-26)28-17-19-38(20-18-28)23-30-24-39(25-32(30)27-13-7-3-8-14-27)34(35(40)41)29-15-9-4-10-16-29/h2-3,5-8,11-14,22,28-30,32,34H,4,9-10,15-21,23-25H2,1H3,(H,40,41)/t30-,32+,34+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP1alpha from human CCR5 expressed in CHO cells |
Eur J Med Chem 43: 2724-34 (2008)
Article DOI: 10.1016/j.ejmech.2008.01.040
BindingDB Entry DOI: 10.7270/Q2G44Q3W |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50141863
((R)-2-((3S,4S)-3-((4-(3-benzyl-1-methyl-1H-pyrazol...)Show SMILES Cn1nc(Cc2ccccc2)cc1C1CCN(C[C@H]2CN(C[C@@H]2c2ccccc2)[C@H](C2CCCCC2)C(O)=O)CC1 |r| Show InChI InChI=1S/C35H46N4O2/c1-37-33(22-31(36-37)21-26-11-5-2-6-12-26)28-17-19-38(20-18-28)23-30-24-39(25-32(30)27-13-7-3-8-14-27)34(35(40)41)29-15-9-4-10-16-29/h2-3,5-8,11-14,22,28-30,32,34H,4,9-10,15-21,23-25H2,1H3,(H,40,41)/t30-,32+,34+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against human CC chemokine receptor 5 |
Bioorg Med Chem Lett 14: 935-9 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.004
BindingDB Entry DOI: 10.7270/Q2PK0FKP |
More data for this
Ligand-Target Pair | |