Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50441742
(CHEMBL2435873)Show SMILES O=C1N(C[C@H](N1C1CCN(Cc2ccc(cc2)N2CCOCC2)CC1)c1ccccc1)C1CCCCC1 |r| Show InChI InChI=1S/C31H42N4O2/c36-31-34(28-9-5-2-6-10-28)24-30(26-7-3-1-4-8-26)35(31)29-15-17-32(18-16-29)23-25-11-13-27(14-12-25)33-19-21-37-22-20-33/h1,3-4,7-8,11-14,28-30H,2,5-6,9-10,15-24H2/t30-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi
Curated by ChEMBL
| Assay Description
Antagonist activity at CCR5 (unknown origin) expressed in HEK293F cell membranes assessed as inhibition of RANTES-induced calcium flux preincubated f... |
J Med Chem 56: 8049-65 (2013)
Article DOI: 10.1021/jm401101p
BindingDB Entry DOI: 10.7270/Q2445NX3 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM50441742
(CHEMBL2435873)Show SMILES O=C1N(C[C@H](N1C1CCN(Cc2ccc(cc2)N2CCOCC2)CC1)c1ccccc1)C1CCCCC1 |r| Show InChI InChI=1S/C31H42N4O2/c36-31-34(28-9-5-2-6-10-28)24-30(26-7-3-1-4-8-26)35(31)29-15-17-32(18-16-29)23-25-11-13-27(14-12-25)33-19-21-37-22-20-33/h1,3-4,7-8,11-14,28-30H,2,5-6,9-10,15-24H2/t30-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 336 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi
Curated by ChEMBL
| Assay Description
Inhibition of CCR5 (unknown origin) expressed in human HeLa cells assessed as inhibition of interaction of CHO cells expressing HIV-1 JRFLenv and HIV... |
J Med Chem 56: 8049-65 (2013)
Article DOI: 10.1021/jm401101p
BindingDB Entry DOI: 10.7270/Q2445NX3 |
More data for this
Ligand-Target Pair | |