Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Lanosterol synthase
(Rattus norvegicus) | BDBM50051372
((6R,8aR)-2-((E)-5,9-Dimethyl-deca-4,8-dienyl)-5,5,...)Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]=[#6]2C([#6])([#6])[#6@H](-[#8])-[#6]-[#6][C@@]2([#6])[#6]-1 |t:14| Show InChI InChI=1S/C24H41NO/c1-19(2)10-9-12-20(3)11-7-8-16-25-17-14-21-23(4,5)22(26)13-15-24(21,6)18-25/h10-11,14,22,26H,7-9,12-13,15-18H2,1-6H3/b20-11+/t22-,24+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA
Curated by ChEMBL
| Assay Description
Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes |
J Med Chem 39: 2302-12 (1996)
Article DOI: 10.1021/jm9504621
BindingDB Entry DOI: 10.7270/Q28G8JTB |
More data for this
Ligand-Target Pair | |
Lanosterol synthase
(Rattus norvegicus) | BDBM50051372
((6R,8aR)-2-((E)-5,9-Dimethyl-deca-4,8-dienyl)-5,5,...)Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]=[#6]2C([#6])([#6])[#6@H](-[#8])-[#6]-[#6][C@@]2([#6])[#6]-1 |t:14| Show InChI InChI=1S/C24H41NO/c1-19(2)10-9-12-20(3)11-7-8-16-25-17-14-21-23(4,5)22(26)13-15-24(21,6)18-25/h10-11,14,22,26H,7-9,12-13,15-18H2,1-6H3/b20-11+/t22-,24+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier SCA
Curated by ChEMBL
| Assay Description
Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes |
J Med Chem 39: 2302-12 (1996)
Article DOI: 10.1021/jm9504621
BindingDB Entry DOI: 10.7270/Q28G8JTB |
More data for this
Ligand-Target Pair | |