Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 361.6 BDBM50051380

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lanosterol synthase (Rattus norvegicus)	BDBM50051380 ((4aS,6S,8aS)-2-((E)-5,9-Dimethyl-deca-4,8-dienyl)-...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#6@@H]2C([#6])([#6])[#6@@H](-[#8])-[#6]-[#6][C@]2([#6])[#6]-1 Show InChI InChI=1S/C24H43NO/c1-19(2)10-9-12-20(3)11-7-8-16-25-17-14-21-23(4,5)22(26)13-15-24(21,6)18-25/h10-11,21-22,26H,7-9,12-18H2,1-6H3/b20-11+/t21-,22+,24-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoires Fournier SCA Curated by ChEMBL					Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase from Rat liver microsomes				J Med Chem 39: 2302-12 (1996) Article DOI: 10.1021/jm9504621 BindingDB Entry DOI: 10.7270/Q28G8JTB
					More data for this Ligand-Target Pair