Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 361.6 BDBM50281893

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lanosterol synthase (Rattus norvegicus)	BDBM50281893 ((4aS,5S,6S,8aS)-5,8a-Dimethyl-2-((E)-1,5,9-trimeth...) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#7]-1-[#6]-[#6]-[#6@H]2-[#6@H](-[#6])-[#6@@H](-[#8])-[#6]-[#6][C@]2([#6])[#6]-1 Show InChI InChI=1S/C24H43NO/c1-18(2)9-7-10-19(3)11-8-12-20(4)25-16-14-22-21(5)23(26)13-15-24(22,6)17-25/h9,11,20-23,26H,7-8,10,12-17H2,1-6H3/b19-11+/t20?,21-,22-,23-,24+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC)				Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83
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