SMILES String Search

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 391.5
BDBM50372557

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50372557 (CHEMBL257040) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nanyang Technological University Curated by ChEMBL					Assay Description Displacement of europium labeled NDP-alpha-MSH from human MC4 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 1223-8 (2008) Article DOI: 10.1016/j.bmcl.2007.11.109 BindingDB Entry DOI: 10.7270/Q2TM7BZM
Nanyang Technological University Curated by ChEMBL					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50372557 (CHEMBL257040) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nanyang Technological University Curated by ChEMBL					Assay Description Displacement of europium labeled NDP-alpha-MSH from human MC3 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 1223-8 (2008) Article DOI: 10.1016/j.bmcl.2007.11.109 BindingDB Entry DOI: 10.7270/Q2TM7BZM
Nanyang Technological University Curated by ChEMBL					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50372557 (CHEMBL257040) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
Nanyang Technological University Curated by ChEMBL					Assay Description Displacement of europium labeled NDP-alpha-MSH from human MC1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 1223-8 (2008) Article DOI: 10.1016/j.bmcl.2007.11.109 BindingDB Entry DOI: 10.7270/Q2TM7BZM
Nanyang Technological University Curated by ChEMBL					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50372557 (CHEMBL257040) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a
Nanyang Technological University Curated by ChEMBL					Assay Description Agonist activity at human MC3 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 1223-8 (2008) Article DOI: 10.1016/j.bmcl.2007.11.109 BindingDB Entry DOI: 10.7270/Q2TM7BZM
Nanyang Technological University Curated by ChEMBL					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50372557 (CHEMBL257040) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Nanyang Technological University Curated by ChEMBL					Assay Description Agonist activity at human MC4 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 1223-8 (2008) Article DOI: 10.1016/j.bmcl.2007.11.109 BindingDB Entry DOI: 10.7270/Q2TM7BZM
Nanyang Technological University Curated by ChEMBL					More data for this Ligand-Target Pair