Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Melanocortin receptor 3
(Mus musculus) | BDBM50258958
(CHEMBL4104582)Show SMILES [H][C@@]12CCCN1C(=O)[C@@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC2=O |r| Show InChI InChI=1S/C52H65N13O8/c1-32-44(66)63-41(28-35-18-9-4-10-19-35)50(72)65-25-13-22-43(65)51(73)64-24-12-21-42(64)49(71)59-37(20-11-23-56-52(53)54)45(67)60-38(26-33-14-5-2-6-15-33)47(69)61-39(27-34-16-7-3-8-17-34)48(70)62-40(46(68)58-32)29-36-30-55-31-57-36/h2-10,14-19,30-32,37-43H,11-13,20-29H2,1H3,(H,55,57)(H,58,68)(H,59,71)(H,60,67)(H,61,69)(H,62,70)(H,63,66)(H4,53,54,56)/t32-,37-,38-,39-,40-,41-,42-,43+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Minnesota
Curated by ChEMBL
| Assay Description
Agonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as increase in cAMP accumulation after 2 hrs by AlphaScreen assa... |
J Med Chem 60: 8103-8114 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00856
BindingDB Entry DOI: 10.7270/Q2DN47H1 |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50258958
(CHEMBL4104582)Show SMILES [H][C@@]12CCCN1C(=O)[C@@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC2=O |r| Show InChI InChI=1S/C52H65N13O8/c1-32-44(66)63-41(28-35-18-9-4-10-19-35)50(72)65-25-13-22-43(65)51(73)64-24-12-21-42(64)49(71)59-37(20-11-23-56-52(53)54)45(67)60-38(26-33-14-5-2-6-15-33)47(69)61-39(27-34-16-7-3-8-17-34)48(70)62-40(46(68)58-32)29-36-30-55-31-57-36/h2-10,14-19,30-32,37-43H,11-13,20-29H2,1H3,(H,55,57)(H,58,68)(H,59,71)(H,60,67)(H,61,69)(H,62,70)(H,63,66)(H4,53,54,56)/t32-,37-,38-,39-,40-,41-,42-,43+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Minnesota
Curated by ChEMBL
| Assay Description
Agonist activity at mouse melanocortin receptor 1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 2 hrs by AlphaScreen assa... |
J Med Chem 60: 8103-8114 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00856
BindingDB Entry DOI: 10.7270/Q2DN47H1 |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50258958
(CHEMBL4104582)Show SMILES [H][C@@]12CCCN1C(=O)[C@@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC2=O |r| Show InChI InChI=1S/C52H65N13O8/c1-32-44(66)63-41(28-35-18-9-4-10-19-35)50(72)65-25-13-22-43(65)51(73)64-24-12-21-42(64)49(71)59-37(20-11-23-56-52(53)54)45(67)60-38(26-33-14-5-2-6-15-33)47(69)61-39(27-34-16-7-3-8-17-34)48(70)62-40(46(68)58-32)29-36-30-55-31-57-36/h2-10,14-19,30-32,37-43H,11-13,20-29H2,1H3,(H,55,57)(H,58,68)(H,59,71)(H,60,67)(H,61,69)(H,62,70)(H,63,66)(H4,53,54,56)/t32-,37-,38-,39-,40-,41-,42-,43+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Minnesota
Curated by ChEMBL
| Assay Description
Agonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as increase in cAMP accumulation after 2 hrs by AlphaScreen assa... |
J Med Chem 60: 8103-8114 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00856
BindingDB Entry DOI: 10.7270/Q2DN47H1 |
More data for this
Ligand-Target Pair | |