Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Opioid growth factor receptor-like protein 1
(Homo sapiens (Human)) | BDBM14328
(US8846929, 249)Show SMILES [H][C@]12COC[C@]([H])(C[C@@]([H])(C1)n1c3ccccc3nc(C(O)=O)c1=O)N2C1CCCCCCC1 |r,TLB:11:8:25:2.4.3| Show InChI InChI=1S/C24H31N3O4/c28-23-22(24(29)30)25-20-10-6-7-11-21(20)27(23)17-12-18-14-31-15-19(13-17)26(18)16-8-4-2-1-3-5-9-16/h6-7,10-11,16-19H,1-5,8-9,12-15H2,(H,29,30)/t17-,18-,19+ | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
Similars
| US Patent
| 260 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma L.P.; Shionogi & Co., Ltd.
US Patent
| Assay Description Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin... |
US Patent US8846929 (2014)
BindingDB Entry DOI: 10.7270/Q2G44P04 |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM14328
(US8846929, 249)Show SMILES [H][C@]12COC[C@]([H])(C[C@@]([H])(C1)n1c3ccccc3nc(C(O)=O)c1=O)N2C1CCCCCCC1 |r,TLB:11:8:25:2.4.3| Show InChI InChI=1S/C24H31N3O4/c28-23-22(24(29)30)25-20-10-6-7-11-21(20)27(23)17-12-18-14-31-15-19(13-17)26(18)16-8-4-2-1-3-5-9-16/h6-7,10-11,16-19H,1-5,8-9,12-15H2,(H,29,30)/t17-,18-,19+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
Similars
| US Patent
| 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma L.P.; Shionogi & Co., Ltd.
US Patent
| Assay Description Radioligand dose displacement assays used 0.4-0.8nM [3H]-U69,593 (NEN; 40 Ci/mmole) with 10-20 ug membrane protein (recombinant kappa opioid receptor... |
US Patent US8846929 (2014)
BindingDB Entry DOI: 10.7270/Q2G44P04 |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM14328
(US8846929, 249)Show SMILES [H][C@]12COC[C@]([H])(C[C@@]([H])(C1)n1c3ccccc3nc(C(O)=O)c1=O)N2C1CCCCCCC1 |r,TLB:11:8:25:2.4.3| Show InChI InChI=1S/C24H31N3O4/c28-23-22(24(29)30)25-20-10-6-7-11-21(20)27(23)17-12-18-14-31-15-19(13-17)26(18)16-8-4-2-1-3-5-9-16/h6-7,10-11,16-19H,1-5,8-9,12-15H2,(H,29,30)/t17-,18-,19+ | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
Similars
| US Patent
| 4.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma L.P.; Shionogi & Co., Ltd.
US Patent
| Assay Description Radioligand dose-displacement binding assays for u-opioid receptors used 0.2nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20mg membrane protein/w... |
US Patent US8846929 (2014)
BindingDB Entry DOI: 10.7270/Q2G44P04 |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM14328
(US8846929, 249)Show SMILES [H][C@]12COC[C@]([H])(C[C@@]([H])(C1)n1c3ccccc3nc(C(O)=O)c1=O)N2C1CCCCCCC1 |r,TLB:11:8:25:2.4.3| Show InChI InChI=1S/C24H31N3O4/c28-23-22(24(29)30)25-20-10-6-7-11-21(20)27(23)17-12-18-14-31-15-19(13-17)26(18)16-8-4-2-1-3-5-9-16/h6-7,10-11,16-19H,1-5,8-9,12-15H2,(H,29,30)/t17-,18-,19+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
Similars
| US Patent
| 5.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma L.P.; Shionogi & Co., Ltd.
US Patent
| Assay Description Radioligand dose-displacement assays used 0.2nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20ug membrane protein (recombinant delta opioid recepto... |
US Patent US8846929 (2014)
BindingDB Entry DOI: 10.7270/Q2G44P04 |
More data for this Ligand-Target Pair | |