Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human)) | BDBM50111175
((2S)-5-[(E)-[amino(azaniumyl)methylidene]amino]-N-...)Show SMILES [NH3+]C(=N)NCCC[C@H](NCc1ccc2ccccc2c1)C(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C27H29N5O/c28-27(29)30-15-5-10-25(31-18-19-11-12-20-6-1-3-8-22(20)16-19)26(33)32-24-14-13-21-7-2-4-9-23(21)17-24/h1-4,6-9,11-14,16-17,25,31H,5,10,15,18H2,(H,32,33)(H4,28,29,30)/p+1/t25-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 1 receptor |
Bioorg Med Chem Lett 12: 1039-42 (2002)
BindingDB Entry DOI: 10.7270/Q2833SKD |
More data for this Ligand-Target Pair | |
Melanocortin receptor 5
(Homo sapiens (Human)) | BDBM50111175
((2S)-5-[(E)-[amino(azaniumyl)methylidene]amino]-N-...)Show SMILES [NH3+]C(=N)NCCC[C@H](NCc1ccc2ccccc2c1)C(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C27H29N5O/c28-27(29)30-15-5-10-25(31-18-19-11-12-20-6-1-3-8-22(20)16-19)26(33)32-24-14-13-21-7-2-4-9-23(21)17-24/h1-4,6-9,11-14,16-17,25,31H,5,10,15,18H2,(H,32,33)(H4,28,29,30)/p+1/t25-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 5 receptor |
Bioorg Med Chem Lett 12: 1039-42 (2002)
BindingDB Entry DOI: 10.7270/Q2833SKD |
More data for this Ligand-Target Pair | |
Melanocortin receptor 3
(Homo sapiens (Human)) | BDBM50111175
((2S)-5-[(E)-[amino(azaniumyl)methylidene]amino]-N-...)Show SMILES [NH3+]C(=N)NCCC[C@H](NCc1ccc2ccccc2c1)C(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C27H29N5O/c28-27(29)30-15-5-10-25(31-18-19-11-12-20-6-1-3-8-22(20)16-19)26(33)32-24-14-13-21-7-2-4-9-23(21)17-24/h1-4,6-9,11-14,16-17,25,31H,5,10,15,18H2,(H,32,33)(H4,28,29,30)/p+1/t25-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 3 receptor |
Bioorg Med Chem Lett 12: 1039-42 (2002)
BindingDB Entry DOI: 10.7270/Q2833SKD |
More data for this Ligand-Target Pair | |
Melanocortin receptor 4
(Homo sapiens (Human)) | BDBM50111175
((2S)-5-[(E)-[amino(azaniumyl)methylidene]amino]-N-...)Show SMILES [NH3+]C(=N)NCCC[C@H](NCc1ccc2ccccc2c1)C(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C27H29N5O/c28-27(29)30-15-5-10-25(31-18-19-11-12-20-6-1-3-8-22(20)16-19)26(33)32-24-14-13-21-7-2-4-9-23(21)17-24/h1-4,6-9,11-14,16-17,25,31H,5,10,15,18H2,(H,32,33)(H4,28,29,30)/p+1/t25-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 4 receptor |
Bioorg Med Chem Lett 12: 1039-42 (2002)
BindingDB Entry DOI: 10.7270/Q2833SKD |
More data for this Ligand-Target Pair | |