Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Lanosterol synthase
(Homo sapiens (Human)) | BDBM50095598
(CHEMBL70223 | [4-(4-Bromo-benzenesulfonyl)-piperaz...)Show SMILES Brc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C1CCN(CC1)c1ccncn1 Show InChI InChI=1S/C20H24BrN5O3S/c21-17-1-3-18(4-2-17)30(28,29)26-13-11-25(12-14-26)20(27)16-6-9-24(10-7-16)19-5-8-22-15-23-19/h1-5,8,15-16H,6-7,9-14H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Compound was tested for its inhibition against human OSC enzyme |
J Med Chem 43: 4964-72 (2001)
BindingDB Entry DOI: 10.7270/Q2WW7GX6 |
More data for this
Ligand-Target Pair | |
Lanosterol synthase
(Rattus norvegicus) | BDBM50095598
(CHEMBL70223 | [4-(4-Bromo-benzenesulfonyl)-piperaz...)Show SMILES Brc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C1CCN(CC1)c1ccncn1 Show InChI InChI=1S/C20H24BrN5O3S/c21-17-1-3-18(4-2-17)30(28,29)26-13-11-25(12-14-26)20(27)16-6-9-24(10-7-16)19-5-8-22-15-23-19/h1-5,8,15-16H,6-7,9-14H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Concentration for the inhibition of rat microsomal oxidosqualene cyclase-lanosterol synthase (OSC) |
Bioorg Med Chem Lett 11: 2213-6 (2001)
BindingDB Entry DOI: 10.7270/Q27080Q7 |
More data for this
Ligand-Target Pair | |
Lanosterol synthase
(Rattus norvegicus) | BDBM50095598
(CHEMBL70223 | [4-(4-Bromo-benzenesulfonyl)-piperaz...)Show SMILES Brc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C1CCN(CC1)c1ccncn1 Show InChI InChI=1S/C20H24BrN5O3S/c21-17-1-3-18(4-2-17)30(28,29)26-13-11-25(12-14-26)20(27)16-6-9-24(10-7-16)19-5-8-22-15-23-19/h1-5,8,15-16H,6-7,9-14H2 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Compound was tested for its inhibition against rat OSC enzyme |
J Med Chem 43: 4964-72 (2001)
BindingDB Entry DOI: 10.7270/Q2WW7GX6 |
More data for this
Ligand-Target Pair | |