Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Branched-chain-amino-acid aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50173937
(CHEMBL3809820)Show SMILES Brc1ccc(s1)C(=O)N[C@H]1CCC[C@H](C1)n1c(nc2ccccc12)-c1ccccn1 |r| Show InChI InChI=1S/C23H21BrN4OS/c24-21-12-11-20(30-21)23(29)26-15-6-5-7-16(14-15)28-19-10-2-1-8-17(19)27-22(28)18-9-3-4-13-25-18/h1-4,8-13,15-16H,5-7,14H2,(H,26,29)/t15-,16+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibition of human BCATm (28 to 392 residues) using L-Leucine and alpha-ketogluterate as substrate assessed as L-glutamate production after 10 mins ... |
ACS Med Chem Lett 7: 379-84 (2016)
Article DOI: 10.1021/acsmedchemlett.5b00389
BindingDB Entry DOI: 10.7270/Q2W097V6 |
More data for this
Ligand-Target Pair | |
Branched-chain-amino-acid aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50173937
(CHEMBL3809820)Show SMILES Brc1ccc(s1)C(=O)N[C@H]1CCC[C@H](C1)n1c(nc2ccccc12)-c1ccccn1 |r| Show InChI InChI=1S/C23H21BrN4OS/c24-21-12-11-20(30-21)23(29)26-15-6-5-7-16(14-15)28-19-10-2-1-8-17(19)27-22(28)18-9-3-4-13-25-18/h1-4,8-13,15-16H,5-7,14H2,(H,26,29)/t15-,16+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | <5.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibition of BCATm in differentiated primary human adipocytes using L-Serine and L-Leucine as substrate after overnight incubation by reverse-phase ... |
ACS Med Chem Lett 7: 379-84 (2016)
Article DOI: 10.1021/acsmedchemlett.5b00389
BindingDB Entry DOI: 10.7270/Q2W097V6 |
More data for this
Ligand-Target Pair | |