Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 388.5 BDBM50335373

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50335373 (1-(3,3,3-Triphenyl-propyl)-1H-benzoimidazole | CHE...) Show SMILES C(CC(c1ccccc1)(c1ccccc1)c1ccccc1)n1cnc2ccccc12 Show InChI InChI=1S/C28H24N2/c1-4-12-23(13-5-1)28(24-14-6-2-7-15-24,25-16-8-3-9-17-25)20-21-30-22-29-26-18-10-11-19-27(26)30/h1-19,22H,20-21H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in hamster V79MZ cells using 11-deoxycorticosterone substrate				ACS Med Chem Lett 2: 2-6 (2011) Article DOI: 10.1021/ml100071j BindingDB Entry DOI: 10.7270/Q28W3DKS
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50335373 (1-(3,3,3-Triphenyl-propyl)-1H-benzoimidazole | CHE...) Show SMILES C(CC(c1ccccc1)(c1ccccc1)c1ccccc1)n1cnc2ccccc12 Show InChI InChI=1S/C28H24N2/c1-4-12-23(13-5-1)28(24-14-6-2-7-15-24,25-16-8-3-9-17-25)20-21-30-22-29-26-18-10-11-19-27(26)30/h1-19,22H,20-21H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in hamster V79MZ cells using 11-deoxycorticosterone substrate				ACS Med Chem Lett 2: 2-6 (2011) Article DOI: 10.1021/ml100071j BindingDB Entry DOI: 10.7270/Q28W3DKS
					More data for this Ligand-Target Pair