Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 279.4 BDBM50085264

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50085264 (1-[3-(4-Benzyl-phenyl)-propyl]-pyrrolidine | CHEMB...) Show SMILES C(CN1CCCC1)Cc1ccc(Cc2ccccc2)cc1 Show InChI InChI=1S/C20H25N/c1-2-7-19(8-3-1)17-20-12-10-18(11-13-20)9-6-16-21-14-4-5-15-21/h1-3,7-8,10-13H,4-6,9,14-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity was determined against Leukotriene A4 hydrolase				J Med Chem 43: 721-35 (2000) BindingDB Entry DOI: 10.7270/Q2CN74MZ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50085264 (1-[3-(4-Benzyl-phenyl)-propyl]-pyrrolidine | CHEMB...) Show SMILES C(CN1CCCC1)Cc1ccc(Cc2ccccc2)cc1 Show InChI InChI=1S/C20H25N/c1-2-7-19(8-3-1)17-20-12-10-18(11-13-20)9-6-16-21-14-4-5-15-21/h1-3,7-8,10-13H,4-6,9,14-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity was determined for LTB4 production in human whole blood.				J Med Chem 43: 721-35 (2000) BindingDB Entry DOI: 10.7270/Q2CN74MZ
					More data for this Ligand-Target Pair