Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 271.3 BDBM50085292

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50085292 (1-[2-(4-Furan-2-ylmethyl-phenoxy)-ethyl]-pyrrolidi...) Show SMILES C(CN1CCCC1)Oc1ccc(Cc2ccco2)cc1 Show InChI InChI=1S/C17H21NO2/c1-2-10-18(9-1)11-13-20-16-7-5-15(6-8-16)14-17-4-3-12-19-17/h3-8,12H,1-2,9-11,13-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity was determined against Leukotriene A4 hydrolase				J Med Chem 43: 721-35 (2000) BindingDB Entry DOI: 10.7270/Q2CN74MZ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50085292 (1-[2-(4-Furan-2-ylmethyl-phenoxy)-ethyl]-pyrrolidi...) Show SMILES C(CN1CCCC1)Oc1ccc(Cc2ccco2)cc1 Show InChI InChI=1S/C17H21NO2/c1-2-10-18(9-1)11-13-20-16-7-5-15(6-8-16)14-17-4-3-12-19-17/h3-8,12H,1-2,9-11,13-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity was determined for LTB4 production in human whole blood.				J Med Chem 43: 721-35 (2000) BindingDB Entry DOI: 10.7270/Q2CN74MZ
					More data for this Ligand-Target Pair