Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50085298
(1-[2-(4-Furan-3-ylmethyl-phenoxy)-ethyl]-pyrrolidi...)Show InChI InChI=1S/C17H21NO2/c1-2-9-18(8-1)10-12-20-17-5-3-15(4-6-17)13-16-7-11-19-14-16/h3-7,11,14H,1-2,8-10,12-13H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibitory activity was determined against Leukotriene A4 hydrolase |
J Med Chem 43: 721-35 (2000)
BindingDB Entry DOI: 10.7270/Q2CN74MZ |
More data for this Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50085298
(1-[2-(4-Furan-3-ylmethyl-phenoxy)-ethyl]-pyrrolidi...)Show InChI InChI=1S/C17H21NO2/c1-2-9-18(8-1)10-12-20-17-5-3-15(4-6-17)13-16-7-11-19-14-16/h3-7,11,14H,1-2,8-10,12-13H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibitory activity was determined for LTB4 production in human whole blood. |
J Med Chem 43: 721-35 (2000)
BindingDB Entry DOI: 10.7270/Q2CN74MZ |
More data for this Ligand-Target Pair | |