Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 307.4 BDBM50085302

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50085302 (1-{2-[4-(2-Phenyl-cyclopropyl)-phenoxy]-ethyl}-pyr...) Show SMILES C(CN1CCCC1)Oc1ccc(cc1)[C@@H]1C[C@H]1c1ccccc1 Show InChI InChI=1S/C21H25NO/c1-2-6-17(7-3-1)20-16-21(20)18-8-10-19(11-9-18)23-15-14-22-12-4-5-13-22/h1-3,6-11,20-21H,4-5,12-16H2/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity was determined against Leukotriene A4 hydrolase				J Med Chem 43: 721-35 (2000) BindingDB Entry DOI: 10.7270/Q2CN74MZ
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