Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 289.3 BDBM50111161Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50111161 (CHEMBL269653 | [2-(1H-Indol-3-yl)-ethyl]-(1H-indol...) Show SMILES C(Cc1c[nH]c2ccccc12)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C19H19N3/c1-3-7-18-16(5-1)14(12-21-18)9-10-20-11-15-13-22-19-8-4-2-6-17(15)19/h1-8,12-13,20-22H,9-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Tested for its binding affinity towards human recombinant Melanocortin 5 receptor by using radioligand binding assay				Bioorg Med Chem Lett 12: 1035-8 (2002) BindingDB Entry DOI: 10.7270/Q2D799RR
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50111161 (CHEMBL269653 | [2-(1H-Indol-3-yl)-ethyl]-(1H-indol...) Show SMILES C(Cc1c[nH]c2ccccc12)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C19H19N3/c1-3-7-18-16(5-1)14(12-21-18)9-10-20-11-15-13-22-19-8-4-2-6-17(15)19/h1-8,12-13,20-22H,9-11H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Tested for its binding affinity towards human recombinant Melanocortin 1 receptor by using radioligand binding assay				Bioorg Med Chem Lett 12: 1035-8 (2002) BindingDB Entry DOI: 10.7270/Q2D799RR
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50111161 (CHEMBL269653 | [2-(1H-Indol-3-yl)-ethyl]-(1H-indol...) Show SMILES C(Cc1c[nH]c2ccccc12)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C19H19N3/c1-3-7-18-16(5-1)14(12-21-18)9-10-20-11-15-13-22-19-8-4-2-6-17(15)19/h1-8,12-13,20-22H,9-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	8.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Tested for its binding affinity towards human recombinant Melanocortin 3 receptor by using radioligand binding assay				Bioorg Med Chem Lett 12: 1035-8 (2002) BindingDB Entry DOI: 10.7270/Q2D799RR
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50111161 (CHEMBL269653 | [2-(1H-Indol-3-yl)-ethyl]-(1H-indol...) Show SMILES C(Cc1c[nH]c2ccccc12)NCc1c[nH]c2ccccc12 Show InChI InChI=1S/C19H19N3/c1-3-7-18-16(5-1)14(12-21-18)9-10-20-11-15-13-22-19-8-4-2-6-17(15)19/h1-8,12-13,20-22H,9-11H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.61E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Tested for its binding affinity towards human recombinant Melanocortin 4 receptor by using radioligand binding assay				Bioorg Med Chem Lett 12: 1035-8 (2002) BindingDB Entry DOI: 10.7270/Q2D799RR
					More data for this Ligand-Target Pair