Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 381.4 BDBM50347877

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interferon-induced, double-stranded RNA-activated protein kinase (Homo sapiens (Human))	BDBM50347877 (CHEMBL1802781) Show SMILES C(Cc1c[nH]c2ccccc12)Nc1nccc(n1)-c1c[nH]nc1-c1ccncc1 Show InChI InChI=1S/C22H19N7/c1-2-4-19-17(3-1)16(13-26-19)7-11-24-22-25-12-8-20(28-22)18-14-27-29-21(18)15-5-9-23-10-6-15/h1-6,8-10,12-14,26H,7,11H2,(H,27,29)(H,24,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assay				Bioorg Med Chem Lett 21: 4108-14 (2011) Article DOI: 10.1016/j.bmcl.2011.04.149 BindingDB Entry DOI: 10.7270/Q2KK9C4H
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