Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cysteinyl leukotriene receptor 1
(GUINEA PIG) | BDBM50013516
(2-{4-[2-(1H-Tetrazol-5-yl)-ethyl]-phenoxymethyl}-q...)Show InChI InChI=1S/C19H17N5O/c1-2-4-18-15(3-1)8-9-16(20-18)13-25-17-10-5-14(6-11-17)7-12-19-21-23-24-22-19/h1-6,8-11H,7,12-13H2,(H,21,22,23,24) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rorer Central Research
Curated by ChEMBL
| Assay Description Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM) |
J Med Chem 33: 1186-94 (1990)
BindingDB Entry DOI: 10.7270/Q2TB15WM |
More data for this Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1/2
(Homo sapiens (Human)) | BDBM50013516
(2-{4-[2-(1H-Tetrazol-5-yl)-ethyl]-phenoxymethyl}-q...)Show InChI InChI=1S/C19H17N5O/c1-2-4-18-15(3-1)8-9-16(20-18)13-25-17-10-5-14(6-11-17)7-12-19-21-23-24-22-19/h1-6,8-11H,7,12-13H2,(H,21,22,23,24) | PDB
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of the spasmogenic activity of LTD4 in guinea pig parenchymal strips. |
J Med Chem 33: 1186-94 (1990)
BindingDB Entry DOI: 10.7270/Q2TB15WM |
More data for this Ligand-Target Pair | |