Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 328.4 BDBM50125428Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50125428 (1-[2-(4-Benzyl-phenoxy)-ethyl]-1H-benzoimidazole |...) Show SMILES C(Cn1cnc2ccccc12)Oc1ccc(Cc2ccccc2)cc1 Show InChI InChI=1S/C22H20N2O/c1-2-6-18(7-3-1)16-19-10-12-20(13-11-19)25-15-14-24-17-23-21-8-4-5-9-22(21)24/h1-13,17H,14-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibition of recombinant human leukotriene A4 hydrolase.				Bioorg Med Chem Lett 13: 1137-9 (2003) BindingDB Entry DOI: 10.7270/Q2891587
					More data for this Ligand-Target Pair