Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 330.3 BDBM50125419

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50125419 (1-[2-(4-Benzyl-phenoxy)-ethyl]-1H-purine | CHEMBL1...) Show SMILES C(Cn1cnc2ncnc2c1)Oc1ccc(Cc2ccccc2)cc1 Show InChI InChI=1S/C20H18N4O/c1-2-4-16(5-3-1)12-17-6-8-18(9-7-17)25-11-10-24-13-19-20(23-15-24)22-14-21-19/h1-9,13-15H,10-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibition of recombinant human leukotriene A4 hydrolase.				Bioorg Med Chem Lett 13: 1137-9 (2003) BindingDB Entry DOI: 10.7270/Q2891587
					More data for this Ligand-Target Pair