Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM326918
(1-[4-(2,3-dihydro-1,4- benzodioxin-2- yl)benzyl]py...)Show InChI InChI=1S/C19H21NO2/c1-2-6-18-17(5-1)21-14-19(22-18)16-9-7-15(8-10-16)13-20-11-3-4-12-20/h1-2,5-10,19H,3-4,11-14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim International GmbH
US Patent
| Assay Description The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ... |
US Patent US9662339 (2017)
BindingDB Entry DOI: 10.7270/Q2GT5Q8D |
More data for this Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM326981
(1-{4-[(2S)-2,3-dihydro-1,4- benzodioxin-2- yl]be...)Show InChI InChI=1S/C19H21NO2/c1-2-6-18-17(5-1)21-14-19(22-18)16-9-7-15(8-10-16)13-20-11-3-4-12-20/h1-2,5-10,19H,3-4,11-14H2/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim International GmbH
US Patent
| Assay Description The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ... |
US Patent US9662339 (2017)
BindingDB Entry DOI: 10.7270/Q2GT5Q8D |
More data for this Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM326985
(1-{4-[(2R)-2,3-dihydro-1,4- benzodioxin-2- yl]be...)Show SMILES C(N1CCCC1)c1ccc(cc1)[C@@H]1COc2ccccc2O1 |r| Show InChI InChI=1S/C19H21NO2/c1-2-6-18-17(5-1)21-14-19(22-18)16-9-7-15(8-10-16)13-20-11-3-4-12-20/h1-2,5-10,19H,3-4,11-14H2/t19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 2.69 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim International GmbH
US Patent
| Assay Description The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ... |
US Patent US9662339 (2017)
BindingDB Entry DOI: 10.7270/Q2GT5Q8D |
More data for this Ligand-Target Pair | |