Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 385.4 BDBM167823

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM167823 (US9073922, 319) Show SMILES C(Nc1cncc(n1)-c1ccnc2[nH]c(cc12)C1CCNCC1)c1cccnc1 Show InChI InChI=1S/C22H23N7/c1-2-15(11-24-6-1)12-27-21-14-25-13-20(28-21)17-5-9-26-22-18(17)10-19(29-22)16-3-7-23-8-4-16/h1-2,5-6,9-11,13-14,16,23H,3-4,7-8,12H2,(H,26,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78
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