Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 363.5 BDBM50317486

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50317486 ((S)-2-((4-(4-(thiophen-3-yl)benzyl)phenoxy)methyl)...) Show SMILES C(Oc1ccc(Cc2ccc(cc2)-c2ccsc2)cc1)[C@@H]1CCCCN1 |r| Show InChI InChI=1S/C23H25NOS/c1-2-13-24-22(3-1)16-25-23-10-6-19(7-11-23)15-18-4-8-20(9-5-18)21-12-14-26-17-21/h4-12,14,17,22,24H,1-3,13,15-16H2/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MS				Bioorg Med Chem Lett 20: 2851-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.047 BindingDB Entry DOI: 10.7270/Q2CC10VD
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