Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50317497
((S)-2-((4-(biphenyl-4-yloxy)phenoxy)methyl)piperid...)Show SMILES C(Oc1ccc(Oc2ccc(cc2)-c2ccccc2)cc1)[C@@H]1CCCCN1 |r| Show InChI InChI=1S/C24H25NO2/c1-2-6-19(7-3-1)20-9-11-23(12-10-20)27-24-15-13-22(14-16-24)26-18-21-8-4-5-17-25-21/h1-3,6-7,9-16,21,25H,4-5,8,17-18H2/t21-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISA |
Bioorg Med Chem Lett 20: 2851-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.047
BindingDB Entry DOI: 10.7270/Q2CC10VD |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50317497
((S)-2-((4-(biphenyl-4-yloxy)phenoxy)methyl)piperid...)Show SMILES C(Oc1ccc(Oc2ccc(cc2)-c2ccccc2)cc1)[C@@H]1CCCCN1 |r| Show InChI InChI=1S/C24H25NO2/c1-2-6-19(7-3-1)20-9-11-23(12-10-20)27-24-15-13-22(14-16-24)26-18-21-8-4-5-17-25-21/h1-3,6-7,9-16,21,25H,4-5,8,17-18H2/t21-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MS |
Bioorg Med Chem Lett 20: 2851-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.03.047
BindingDB Entry DOI: 10.7270/Q2CC10VD |
More data for this
Ligand-Target Pair | |