Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM50378938
(CHEMBL2011254 | US9394290, 24)Show InChI InChI=1S/C19H15N3/c1-2-4-17-11-18(7-6-16(17)3-1)19-8-5-15(12-21-19)13-22-10-9-20-14-22/h1-12,14H,13H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 246 | n/a | n/a | n/a | n/a | n/a | 37 |
UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN
US Patent
| Assay Description V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w... |
US Patent US9394290 (2016)
BindingDB Entry DOI: 10.7270/Q24T6H86 |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM50378938
(CHEMBL2011254 | US9394290, 24)Show InChI InChI=1S/C19H15N3/c1-2-4-17-11-18(7-6-16(17)3-1)19-8-5-15(12-21-19)13-22-10-9-20-14-22/h1-12,14H,13H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 246 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detector |
ACS Med Chem Lett 2: 559-564 (2011)
Article DOI: 10.1021/ml100283h BindingDB Entry DOI: 10.7270/Q21R6RJ2 |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM50378938
(CHEMBL2011254 | US9394290, 24)Show InChI InChI=1S/C19H15N3/c1-2-4-17-11-18(7-6-16(17)3-1)19-8-5-15(12-21-19)13-22-10-9-20-14-22/h1-12,14H,13H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 782 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detector |
ACS Med Chem Lett 2: 559-564 (2011)
Article DOI: 10.1021/ml100283h BindingDB Entry DOI: 10.7270/Q21R6RJ2 |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM50378938
(CHEMBL2011254 | US9394290, 24)Show InChI InChI=1S/C19H15N3/c1-2-4-17-11-18(7-6-16(17)3-1)19-8-5-15(12-21-19)13-22-10-9-20-14-22/h1-12,14H,13H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 782 | n/a | n/a | n/a | n/a | n/a | 37 |
UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN
US Patent
| Assay Description V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w... |
US Patent US9394290 (2016)
BindingDB Entry DOI: 10.7270/Q24T6H86 |
More data for this Ligand-Target Pair | |