Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein-glutamine gamma-glutamyltransferase 2
(Homo sapiens (Human)) | BDBM50461631
(CHEMBL4225490)Show SMILES C=CC(=O)NCCCC[C@H](NC(=O)Cc1ccccc1)C(=O)N1CCN(CC1)c1ccccn1 |r| Show InChI InChI=1S/C26H33N5O3/c1-2-24(32)28-15-8-6-12-22(29-25(33)20-21-10-4-3-5-11-21)26(34)31-18-16-30(17-19-31)23-13-7-9-14-27-23/h2-5,7,9-11,13-14,22H,1,6,8,12,15-20H2,(H,28,32)(H,29,33)/t22-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 8.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
| Assay Description
Reversible inhibition of human TGase 2 using Z-Glu(HMC)-Gly-OH as substrate measured at 20 secs interval over 900 secs by fluorimetric assay |
J Med Chem 61: 4528-4560 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00286
BindingDB Entry DOI: 10.7270/Q2W66PC7 |
More data for this
Ligand-Target Pair | |
Protein-glutamine gamma-glutamyltransferase 2
(Homo sapiens (Human)) | BDBM50461631
(CHEMBL4225490)Show SMILES C=CC(=O)NCCCC[C@H](NC(=O)Cc1ccccc1)C(=O)N1CCN(CC1)c1ccccn1 |r| Show InChI InChI=1S/C26H33N5O3/c1-2-24(32)28-15-8-6-12-22(29-25(33)20-21-10-4-3-5-11-21)26(34)31-18-16-30(17-19-31)23-13-7-9-14-27-23/h2-5,7,9-11,13-14,22H,1,6,8,12,15-20H2,(H,28,32)(H,29,33)/t22-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
| Assay Description
Inhibition of human TGase 2 using R-I-Cad/DMC as substrate preincubated for 5 mins followed by substrate addition measured at 30 secs interval over 9... |
J Med Chem 61: 4528-4560 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00286
BindingDB Entry DOI: 10.7270/Q2W66PC7 |
More data for this
Ligand-Target Pair | |