Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 556.5 BDBM50211150

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50211150 ((R)-N-(2-(dimethylamino)ethyl)-N-(1-(3-(4-fluoroph...) Show SMILES C[C@@H](N(CCN(C)C)C(=O)Cc1ccc(OC(F)(F)F)cc1)c1nc2ccccc2c(=O)n1-c1ccc(F)cc1 Show InChI InChI=1S/C29H28F4N4O3/c1-19(27-34-25-7-5-4-6-24(25)28(39)37(27)22-12-10-21(30)11-13-22)36(17-16-35(2)3)26(38)18-20-8-14-23(15-9-20)40-29(31,32)33/h4-15,19H,16-18H2,1-3H3/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMC				Bioorg Med Chem Lett 17: 3339-43 (2007) Article DOI: 10.1016/j.bmcl.2007.03.106 BindingDB Entry DOI: 10.7270/Q2VT1SXN
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