Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 534.6 BDBM50211139

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50211139 (CHEMBL395771 | biphenyl-4-carboxylic acid (2-dimet...) Show SMILES C[C@@H](N(CCN(C)C)C(=O)c1ccc(cc1)-c1ccccc1)c1nc2ccccc2c(=O)n1-c1ccc(F)cc1 Show InChI InChI=1S/C33H31FN4O2/c1-23(31-35-30-12-8-7-11-29(30)33(40)38(31)28-19-17-27(34)18-20-28)37(22-21-36(2)3)32(39)26-15-13-25(14-16-26)24-9-5-4-6-10-24/h4-20,23H,21-22H2,1-3H3/t23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMC				Bioorg Med Chem Lett 17: 3339-43 (2007) Article DOI: 10.1016/j.bmcl.2007.03.106 BindingDB Entry DOI: 10.7270/Q2VT1SXN
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