Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 305.3 BDBM50543328

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50543328 (CHEMBL4640214) Show SMILES C[C@@H](N)C(=O)Nc1nc(C(C)=O)c(s1)-c1cncc(N)c1 |r| Show InChI InChI=1S/C13H15N5O2S/c1-6(14)12(20)18-13-17-10(7(2)19)11(21-13)8-3-9(15)5-16-4-8/h3-6H,14-15H2,1-2H3,(H,17,18,20)/t6-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Zurich Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged ATAD2 bromodomain (981 to 1146 residues) expressed in Escherichia coli using biotinylated pepti...				ACS Med Chem Lett 11: 1573-1580 (2020) Article DOI: 10.1021/acsmedchemlett.0c00080 BindingDB Entry DOI: 10.7270/Q2C25101
					More data for this Ligand-Target Pair				3D Structure (crystal)