Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 594.6 BDBM363196

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM363196 ((2R,3R)-2-((2-((3-cyanobenzyl)oxy)-4-((3-(2,3-dihy...) Show SMILES C[C@@H](O)[C@@H](NCc1ccc(OCc2cccc(c2C)-c2ccc3OCCOc3c2)cc1OCc1cccc(c1)C#N)C(O)=O |r| Show InChI InChI=1S/C35H34N2O7/c1-22-28(7-4-8-30(22)26-10-12-31-33(16-26)42-14-13-41-31)21-43-29-11-9-27(19-37-34(23(2)38)35(39)40)32(17-29)44-20-25-6-3-5-24(15-25)18-36/h3-12,15-17,23,34,37-38H,13-14,19-21H2,1-2H3,(H,39,40)/t23-,34-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...				US Patent US9850225 (2017) BindingDB Entry DOI: 10.7270/Q2N018TZ
					More data for this Ligand-Target Pair