Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50269150
(CHEMBL4098787)Show SMILES C[C@@H](O)[C@H](NC(=O)C(C)(C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1CCCN1C(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1CCCCC1)C(N)=O |r| Show InChI InChI=1S/C81H138N28O20/c1-43(112)63(75(127)100-51(26-16-32-94-80(89)90)65(117)98-52(28-29-61(82)114)68(120)97-49(24-14-30-92-78(85)86)66(118)101-53(64(84)116)34-45-18-8-5-9-19-45)107-77(129)81(3,4)108-73(125)58(40-110)106-72(124)57(38-62(83)115)105-70(122)55(36-47-22-12-7-13-23-47)102-69(121)54(35-46-20-10-6-11-21-46)103-71(123)56(37-48-39-91-42-95-48)104-67(119)50(25-15-31-93-79(87)88)99-74(126)60-27-17-33-109(60)76(128)59(41-111)96-44(2)113/h39,42-43,45-47,49-60,63,110-112H,5-38,40-41H2,1-4H3,(H2,82,114)(H2,83,115)(H2,84,116)(H,91,95)(H,96,113)(H,97,120)(H,98,117)(H,99,126)(H,100,127)(H,101,118)(H,102,121)(H,103,123)(H,104,119)(H,105,122)(H,106,124)(H,107,129)(H,108,125)(H4,85,86,92)(H4,87,88,93)(H4,89,90,94)/t43-,49+,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60-,63+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [125I]peptide YY from human Y2 receptor expressed in CHO cell membranes after 60 mins by TopCount scintillation counting analysis |
Bioorg Med Chem Lett 27: 3829-3832 (2017)
Article DOI: 10.1016/j.bmcl.2017.06.055
BindingDB Entry DOI: 10.7270/Q2MK6GC2 |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50269150
(CHEMBL4098787)Show SMILES C[C@@H](O)[C@H](NC(=O)C(C)(C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1CCCN1C(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1CCCCC1)C(N)=O |r| Show InChI InChI=1S/C81H138N28O20/c1-43(112)63(75(127)100-51(26-16-32-94-80(89)90)65(117)98-52(28-29-61(82)114)68(120)97-49(24-14-30-92-78(85)86)66(118)101-53(64(84)116)34-45-18-8-5-9-19-45)107-77(129)81(3,4)108-73(125)58(40-110)106-72(124)57(38-62(83)115)105-70(122)55(36-47-22-12-7-13-23-47)102-69(121)54(35-46-20-10-6-11-21-46)103-71(123)56(37-48-39-91-42-95-48)104-67(119)50(25-15-31-93-79(87)88)99-74(126)60-27-17-33-109(60)76(128)59(41-111)96-44(2)113/h39,42-43,45-47,49-60,63,110-112H,5-38,40-41H2,1-4H3,(H2,82,114)(H2,83,115)(H2,84,116)(H,91,95)(H,96,113)(H,97,120)(H,98,117)(H,99,126)(H,100,127)(H,101,118)(H,102,121)(H,103,123)(H,104,119)(H,105,122)(H,106,124)(H,107,129)(H,108,125)(H4,85,86,92)(H4,87,88,93)(H4,89,90,94)/t43-,49+,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60-,63+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd.
Curated by ChEMBL
| Assay Description
Agonist activity at human Y2 receptor expressed in CHO cell membranes after 120 mins by [35S]GTPgammaS binding assay |
Bioorg Med Chem Lett 27: 3829-3832 (2017)
Article DOI: 10.1016/j.bmcl.2017.06.055
BindingDB Entry DOI: 10.7270/Q2MK6GC2 |
More data for this
Ligand-Target Pair | |