Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 225.3 BDBM50003031

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lanosterol synthase (Rattus norvegicus)	BDBM50003031 (1-(6-Hydroxy-5,8a-dimethyl-octahydro-isoquinolin-2...) Show SMILES C[C@@H]1[C@@H](O)CC[C@]2(C)CN(CC[C@@H]12)C(C)=O Show InChI InChI=1S/C13H23NO2/c1-9-11-5-7-14(10(2)15)8-13(11,3)6-4-12(9)16/h9,11-12,16H,4-8H2,1-3H3/t9-,11-,12-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Marion Merrell Dow Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver				J Med Chem 35: 3581-3 (1992) BindingDB Entry DOI: 10.7270/Q24T6H9N
					More data for this Ligand-Target Pair