Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human)) | BDBM286299
(US11220518, Ex. No. H7 | US11780853, Example H7 | ...)Show SMILES C[C@@H]1CN([C@@H](C)CN1C1CCOCC1)C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C24H35FN8O2/c1-14-12-32(15(2)11-31(14)17-6-8-35-9-7-17)23(34)33-13-18-20(24(33,4)5)29-30-21(18)28-22-19(25)10-26-16(3)27-22/h10,14-15,17H,6-9,11-13H2,1-5H3,(H2,26,27,28,29,30)/t14-,15+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
PFIZER INC.
US Patent
| Assay Description
Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe... |
US Patent US9518060 (2016)
BindingDB Entry DOI: 10.7270/Q2ZK5JPN |
More data for this
Ligand-Target Pair | |
Protein kinase C beta type Isoform 2
(Homo sapiens (Human)) | BDBM286299
(US11220518, Ex. No. H7 | US11780853, Example H7 | ...)Show SMILES C[C@@H]1CN([C@@H](C)CN1C1CCOCC1)C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C24H35FN8O2/c1-14-12-32(15(2)11-31(14)17-6-8-35-9-7-17)23(34)33-13-18-20(24(33,4)5)29-30-21(18)28-22-19(25)10-26-16(3)27-22/h10,14-15,17H,6-9,11-13H2,1-5H3,(H2,26,27,28,29,30)/t14-,15+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Protein kinase C beta type
(Homo sapiens (Human)) | BDBM286299
(US11220518, Ex. No. H7 | US11780853, Example H7 | ...)Show SMILES C[C@@H]1CN([C@@H](C)CN1C1CCOCC1)C(=O)N1Cc2c(Nc3nc(C)ncc3F)n[nH]c2C1(C)C |r| Show InChI InChI=1S/C24H35FN8O2/c1-14-12-32(15(2)11-31(14)17-6-8-35-9-7-17)23(34)33-13-18-20(24(33,4)5)29-30-21(18)28-22-19(25)10-26-16(3)27-22/h10,14-15,17H,6-9,11-13H2,1-5H3,(H2,26,27,28,29,30)/t14-,15+/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q28S4T3T |
More data for this
Ligand-Target Pair | |