Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Baculoviral IAP repeat-containing protein 2
(Homo sapiens (Human)) | BDBM155992
(US9018214, 43)Show SMILES C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ccc(cc23)S(=O)(=O)c2ccccc2)CCN1 |r| Show InChI InChI=1S/C23H29N3O3S/c1-17-14-25(12-11-24-17)15-22(27)26-16-23(2,3)20-10-9-19(13-21(20)26)30(28,29)18-7-5-4-6-8-18/h4-10,13,17,24H,11-12,14-16H2,1-3H3/t17-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astex Therapeutics Limited
US Patent
| Assay Description
Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain... |
US Patent US9018214 (2015)
BindingDB Entry DOI: 10.7270/Q23T9FXQ |
More data for this
Ligand-Target Pair | |
E3 ubiquitin-protein ligase XIAP
(Homo sapiens (Human)) | BDBM155992
(US9018214, 43)Show SMILES C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ccc(cc23)S(=O)(=O)c2ccccc2)CCN1 |r| Show InChI InChI=1S/C23H29N3O3S/c1-17-14-25(12-11-24-17)15-22(27)26-16-23(2,3)20-10-9-19(13-21(20)26)30(28,29)18-7-5-4-6-8-18/h4-10,13,17,24H,11-12,14-16H2,1-3H3/t17-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 640 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Astex Therapeutics Limited
US Patent
| Assay Description
Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain... |
US Patent US9018214 (2015)
BindingDB Entry DOI: 10.7270/Q23T9FXQ |
More data for this
Ligand-Target Pair | |