Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50436502
(CHEMBL2397368)Show SMILES C[C@@H]1CN(CCN1C(=O)C12CC3CC(CC(C3)C1)C2)c1cccnc1 |r,TLB:7:9:12.11.16:14,THB:10:11:14:18.9.17,10:9:12.11.16:14,17:9:12:16.15.14,17:15:12:18.10.9,7:9:12:16.15.14| Show InChI InChI=1S/C21H29N3O/c1-15-14-23(19-3-2-4-22-13-19)5-6-24(15)20(25)21-10-16-7-17(11-21)9-18(8-16)12-21/h2-4,13,15-18H,5-12,14H2,1H3/t15-,16?,17?,18?,21?/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 596 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human mGluR1 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium mobilization |
Bioorg Med Chem Lett 23: 3713-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.05.020
BindingDB Entry DOI: 10.7270/Q2Z60QGB |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50436502
(CHEMBL2397368)Show SMILES C[C@@H]1CN(CCN1C(=O)C12CC3CC(CC(C3)C1)C2)c1cccnc1 |r,TLB:7:9:12.11.16:14,THB:10:11:14:18.9.17,10:9:12.11.16:14,17:9:12:16.15.14,17:15:12:18.10.9,7:9:12:16.15.14| Show InChI InChI=1S/C21H29N3O/c1-15-14-23(19-3-2-4-22-13-19)5-6-24(15)20(25)21-10-16-7-17(11-21)9-18(8-16)12-21/h2-4,13,15-18H,5-12,14H2,1H3/t15-,16?,17?,18?,21?/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 603 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human mGluR1 expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium mobilization |
Bioorg Med Chem Lett 23: 3713-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.05.020
BindingDB Entry DOI: 10.7270/Q2Z60QGB |
More data for this
Ligand-Target Pair | |