Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 467.5 BDBM389785

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM389785 (2-Imidazo[4,5-b]pyridin-3-yl-1-[(R)-2-methyl-4-(2-...) Show SMILES C[C@@H]1CN(CCN1C(=O)Cn1cnc2cccnc12)C1N(CCc2ccccc12)c1ccccn1 Show InChI InChI=1S/C27H29N7O/c1-20-17-31(15-16-33(20)25(35)18-32-19-30-23-9-6-13-29-26(23)32)27-22-8-3-2-7-21(22)11-14-34(27)24-10-4-5-12-28-24/h2-10,12-13,19-20,27H,11,14-18H2,1H3/t20-,27?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.71	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...				Bioorg Med Chem Lett 17: 3473-9 (2007) BindingDB Entry DOI: 10.7270/Q20R9RRK
					More data for this Ligand-Target Pair