Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 566.5 BDBM389793

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM389793 (2-Imidazo[4,5-b]pyridin-3-yl-1-((R)-2-methyl-4-{2-...) Show SMILES C[C@@H]1CN(CCN1C(=O)Cn1cnc2cccnc12)c1cccc2CCN(Cc12)c1cnc(OCC(F)(F)F)nc1 Show InChI InChI=1S/C28H29F3N8O2/c1-19-14-37(10-11-39(19)25(40)16-38-18-35-23-5-3-8-32-26(23)38)24-6-2-4-20-7-9-36(15-22(20)24)21-12-33-27(34-13-21)41-17-28(29,30)31/h2-6,8,12-13,18-19H,7,9-11,14-17H2,1H3/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.98	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...				Bioorg Med Chem Lett 17: 3473-9 (2007) BindingDB Entry DOI: 10.7270/Q20R9RRK
					More data for this Ligand-Target Pair