Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 536.5 BDBM389788

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM389788 (2-Imidazo[4,5-b]pyridin-3-yl-1-{(R)-2-methyl-4-[2-...) Show SMILES C[C@@H]1CN(CCN1C(=O)Cn1cnc2cccnc12)c1cccc2CCN(Cc12)c1cnc(nc1)C(F)(F)F Show InChI InChI=1S/C27H27F3N8O/c1-18-14-36(10-11-38(18)24(39)16-37-17-34-22-5-3-8-31-25(22)37)23-6-2-4-19-7-9-35(15-21(19)23)20-12-32-26(33-13-20)27(28,29)30/h2-6,8,12-13,17-18H,7,9-11,14-16H2,1H3/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.74	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...				Bioorg Med Chem Lett 17: 3473-9 (2007) BindingDB Entry DOI: 10.7270/Q20R9RRK
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