Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 482.5 BDBM389789

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM389789 (2-Imidazo[4,5-b]pyridin-3-yl-1-{(R)-2-methyl-4-[2-...) Show SMILES C[C@@H]1CN(CCN1C(=O)Cn1cnc2cccnc12)c1cccc2CCN(Cc12)c1ncc(C)cn1 Show InChI InChI=1S/C27H30N8O/c1-19-13-29-27(30-14-19)33-10-8-21-5-3-7-24(22(21)16-33)32-11-12-35(20(2)15-32)25(36)17-34-18-31-23-6-4-9-28-26(23)34/h3-7,9,13-14,18,20H,8,10-12,15-17H2,1-2H3/t20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32.6	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...				Bioorg Med Chem Lett 17: 3473-9 (2007) BindingDB Entry DOI: 10.7270/Q20R9RRK
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