Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM208767
(US9266876, 234)Show SMILES C[C@@H]1CN(CCN1C(=O)Cn1nc(C)nc1C)c1sc(nc1-c1nc2ccc(cc2[nH]1)-n1cncn1)C(F)(F)F Show InChI InChI=1S/C24H24F3N11OS/c1-13-9-35(6-7-36(13)19(39)10-37-15(3)30-14(2)34-37)22-20(33-23(40-22)24(25,26)27)21-31-17-5-4-16(8-18(17)32-21)38-12-28-11-29-38/h4-5,8,11-13H,6-7,9-10H2,1-3H3,(H,31,32)/t13-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00676
BindingDB Entry DOI: 10.7270/Q2222ZSK |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3/Guanine nucleotide-binding protein subunit alpha-15
(Homo sapiens (Human)) | BDBM208767
(US9266876, 234)Show SMILES C[C@@H]1CN(CCN1C(=O)Cn1nc(C)nc1C)c1sc(nc1-c1nc2ccc(cc2[nH]1)-n1cncn1)C(F)(F)F Show InChI InChI=1S/C24H24F3N11OS/c1-13-9-35(6-7-36(13)19(39)10-37-15(3)30-14(2)34-37)22-20(33-23(40-22)24(25,26)27)21-31-17-5-4-16(8-18(17)32-21)38-12-28-11-29-38/h4-5,8,11-13H,6-7,9-10H2,1-3H3,(H,31,32)/t13-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Actelion Pharmaceuticals Ltd.
US Patent
| Assay Description
The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the... |
US Patent US9266876 (2016)
BindingDB Entry DOI: 10.7270/Q2DB80NB |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM208767
(US9266876, 234)Show SMILES C[C@@H]1CN(CCN1C(=O)Cn1nc(C)nc1C)c1sc(nc1-c1nc2ccc(cc2[nH]1)-n1cncn1)C(F)(F)F Show InChI InChI=1S/C24H24F3N11OS/c1-13-9-35(6-7-36(13)19(39)10-37-15(3)30-14(2)34-37)22-20(33-23(40-22)24(25,26)27)21-31-17-5-4-16(8-18(17)32-21)38-12-28-11-29-38/h4-5,8,11-13H,6-7,9-10H2,1-3H3,(H,31,32)/t13-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00676
BindingDB Entry DOI: 10.7270/Q2222ZSK |
More data for this
Ligand-Target Pair | |