Found 6 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM295071
((R)-5-(2-methyl-5-((3- methylmorpholino)sulfon- yl...)Show SMILES C[C@@H]1COCCN1S(=O)(=O)c1ccc(C)c(c1)-c1cnc(N)c(c1)-c1cc(C)no1 |r| Show InChI InChI=1S/C21H24N4O4S/c1-13-4-5-17(30(26,27)25-6-7-28-12-15(25)3)10-18(13)16-9-19(21(22)23-11-16)20-8-14(2)24-29-20/h4-5,8-11,15H,6-7,12H2,1-3H3,(H2,22,23)/t15-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Novartis AG
US Patent
| Assay Description
The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad, Calif., USA) (Cat. No. PV5099). The kit contains t... |
US Patent US10112926 (2018)
BindingDB Entry DOI: 10.7270/Q22R3TQ9 |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha
(Homo sapiens (Human)) | BDBM295071
((R)-5-(2-methyl-5-((3- methylmorpholino)sulfon- yl...)Show SMILES C[C@@H]1COCCN1S(=O)(=O)c1ccc(C)c(c1)-c1cnc(N)c(c1)-c1cc(C)no1 |r| Show InChI InChI=1S/C21H24N4O4S/c1-13-4-5-17(30(26,27)25-6-7-28-12-15(25)3)10-18(13)16-9-19(21(22)23-11-16)20-8-14(2)24-29-20/h4-5,8-11,15H,6-7,12H2,1-3H3,(H2,22,23)/t15-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Novartis AG
US Patent
| Assay Description
The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit... |
US Patent US10112926 (2018)
BindingDB Entry DOI: 10.7270/Q22R3TQ9 |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM295071
((R)-5-(2-methyl-5-((3- methylmorpholino)sulfon- yl...)Show SMILES C[C@@H]1COCCN1S(=O)(=O)c1ccc(C)c(c1)-c1cnc(N)c(c1)-c1cc(C)no1 |r| Show InChI InChI=1S/C21H24N4O4S/c1-13-4-5-17(30(26,27)25-6-7-28-12-15(25)3)10-18(13)16-9-19(21(22)23-11-16)20-8-14(2)24-29-20/h4-5,8-11,15H,6-7,12H2,1-3H3,(H2,22,23)/t15-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Novartis AG
US Patent
| Assay Description
The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad, Calif., USA) (Cat. No. PV5099). The kit contains t... |
US Patent US10112926 (2018)
BindingDB Entry DOI: 10.7270/Q22R3TQ9 |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4-kinase beta
(Homo sapiens (Human)) | BDBM295071
((R)-5-(2-methyl-5-((3- methylmorpholino)sulfon- yl...)Show SMILES C[C@@H]1COCCN1S(=O)(=O)c1ccc(C)c(c1)-c1cnc(N)c(c1)-c1cc(C)no1 |r| Show InChI InChI=1S/C21H24N4O4S/c1-13-4-5-17(30(26,27)25-6-7-28-12-15(25)3)10-18(13)16-9-19(21(22)23-11-16)20-8-14(2)24-29-20/h4-5,8-11,15H,6-7,12H2,1-3H3,(H2,22,23)/t15-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Novartis AG
US Patent
| Assay Description
The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit... |
US Patent US10112926 (2018)
BindingDB Entry DOI: 10.7270/Q22R3TQ9 |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human)) | BDBM295071
((R)-5-(2-methyl-5-((3- methylmorpholino)sulfon- yl...)Show SMILES C[C@@H]1COCCN1S(=O)(=O)c1ccc(C)c(c1)-c1cnc(N)c(c1)-c1cc(C)no1 |r| Show InChI InChI=1S/C21H24N4O4S/c1-13-4-5-17(30(26,27)25-6-7-28-12-15(25)3)10-18(13)16-9-19(21(22)23-11-16)20-8-14(2)24-29-20/h4-5,8-11,15H,6-7,12H2,1-3H3,(H2,22,23)/t15-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Novartis AG
US Patent
| Assay Description
The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit... |
US Patent US10112926 (2018)
BindingDB Entry DOI: 10.7270/Q22R3TQ9 |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase catalytic subunit type 3
(Homo sapiens (Human)) | BDBM295071
((R)-5-(2-methyl-5-((3- methylmorpholino)sulfon- yl...)Show SMILES C[C@@H]1COCCN1S(=O)(=O)c1ccc(C)c(c1)-c1cnc(N)c(c1)-c1cc(C)no1 |r| Show InChI InChI=1S/C21H24N4O4S/c1-13-4-5-17(30(26,27)25-6-7-28-12-15(25)3)10-18(13)16-9-19(21(22)23-11-16)20-8-14(2)24-29-20/h4-5,8-11,15H,6-7,12H2,1-3H3,(H2,22,23)/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Novartis AG
US Patent
| Assay Description
The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit... |
US Patent US10112926 (2018)
BindingDB Entry DOI: 10.7270/Q22R3TQ9 |
More data for this
Ligand-Target Pair | |