Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 409.4 BDBM577573

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human))	BDBM577573 (2-((1-(Methyl-d3)-3-(((2R,3R)-2-methyloxetan-3-yl)...) Show SMILES C[C@@H]1OC[C@@H]1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM577573 (2-((1-(Methyl-d3)-3-(((2R,3R)-2-methyloxetan-3-yl)...) Show SMILES C[C@@H]1OC[C@@H]1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022263472	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S75KKQ
					More data for this Ligand-Target Pair