Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-lactamase TEM
(Escherichia coli) | BDBM50076681
(CHEMBL6469 | Sodium; (2S,3S,5R,6R)-3-((Z)-2-cyano-...)Show SMILES C[C@]1(\C=C/C#N)[C@@H](N2[C@@H]([C@H](CO)C2=O)S1(=O)=O)C([O-])=O Show InChI InChI=1S/C11H12N2O6S/c1-11(3-2-4-12)7(10(16)17)13-8(15)6(5-14)9(13)20(11,18)19/h2-3,6-7,9,14H,5H2,1H3,(H,16,17)/p-1/b3-2-/t6-,7+,9-,11+/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description Inhibitory activity of the compound against TEM-1 (class A) beta-lactamase |
Bioorg Med Chem Lett 9: 997-1002 (1999)
BindingDB Entry DOI: 10.7270/Q2PK0FBJ |
More data for this Ligand-Target Pair | |
Beta-lactamase
(Escherichia coli) | BDBM50076681
(CHEMBL6469 | Sodium; (2S,3S,5R,6R)-3-((Z)-2-cyano-...)Show SMILES C[C@]1(\C=C/C#N)[C@@H](N2[C@@H]([C@H](CO)C2=O)S1(=O)=O)C([O-])=O Show InChI InChI=1S/C11H12N2O6S/c1-11(3-2-4-12)7(10(16)17)13-8(15)6(5-14)9(13)20(11,18)19/h2-3,6-7,9,14H,5H2,1H3,(H,16,17)/p-1/b3-2-/t6-,7+,9-,11+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description Inhibitory activity of the compound against AmpC (class C) beta-lactamase |
Bioorg Med Chem Lett 9: 997-1002 (1999)
BindingDB Entry DOI: 10.7270/Q2PK0FBJ |
More data for this Ligand-Target Pair | |