Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM445046
(US10668167, Compound 58)Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Cc2ccc(O)c(N)c2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C35H37F2NO7/c1-32-10-9-21(40)13-24(32)25(36)14-23-22-15-30-35(29(43)17-39,33(22,2)16-28(42)34(23,32)37)45-31(44-30)20-6-3-18(4-7-20)11-19-5-8-27(41)26(38)12-19/h3-10,12-13,22-23,25,28,30-31,39,41-42H,11,14-17,38H2,1-2H3/t22-,23-,25-,28-,30+,31+,32-,33-,34-,35+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.
US Patent
| Assay Description
Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15... |
US Patent US10668167 (2020)
BindingDB Entry DOI: 10.7270/Q2B56NSW |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM445046
(US10668167, Compound 58)Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Cc2ccc(O)c(N)c2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C35H37F2NO7/c1-32-10-9-21(40)13-24(32)25(36)14-23-22-15-30-35(29(43)17-39,33(22,2)16-28(42)34(23,32)37)45-31(44-30)20-6-3-18(4-7-20)11-19-5-8-27(41)26(38)12-19/h3-10,12-13,22-23,25,28,30-31,39,41-42H,11,14-17,38H2,1-2H3/t22-,23-,25-,28-,30+,31+,32-,33-,34-,35+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 34.1 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.
US Patent
| Assay Description
Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat... |
US Patent US10668167 (2020)
BindingDB Entry DOI: 10.7270/Q2B56NSW |
More data for this
Ligand-Target Pair | |
Estrogen receptor
(Homo sapiens (Human)) | BDBM445046
(US10668167, Compound 58)Show SMILES C[C@]12C[C@H](O)[C@@]3(F)[C@@H](C[C@H](F)C4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Cc2ccc(O)c(N)c2)cc1 |r,c:15,t:11| Show InChI InChI=1S/C35H37F2NO7/c1-32-10-9-21(40)13-24(32)25(36)14-23-22-15-30-35(29(43)17-39,33(22,2)16-28(42)34(23,32)37)45-31(44-30)20-6-3-18(4-7-20)11-19-5-8-27(41)26(38)12-19/h3-10,12-13,22-23,25,28,30-31,39,41-42H,11,14-17,38H2,1-2H3/t22-,23-,25-,28-,30+,31+,32-,33-,34-,35+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 5.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.
US Patent
| Assay Description
Small molecules were tested for estrogen receptor (ER) alpha binding using a modification of the LanthaScreen® TR-FRET Estrogen Receptor Alpha Coacti... |
US Patent US10668167 (2020)
BindingDB Entry DOI: 10.7270/Q2B56NSW |
More data for this
Ligand-Target Pair | |