Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM445038
(US10668167, Compound 48)Show SMILES C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Cc2ccc(O)c(N)c2)cc1 |r,c:13,t:9| Show InChI InChI=1S/C35H39NO7/c1-33-12-11-23(38)15-22(33)8-9-24-25-16-30-35(29(41)18-37,34(25,2)17-28(40)31(24)33)43-32(42-30)21-6-3-19(4-7-21)13-20-5-10-27(39)26(36)14-20/h3-7,10-12,14-15,24-25,28,30-32,37,39-40H,8-9,13,16-18,36H2,1-2H3/t24-,25-,28-,30+,31+,32+,33-,34-,35+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 11.8 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.
US Patent
| Assay Description
Small molecules were tested for glucocorticoid receptor (GR) binding using the Polarscreen™ Glucocorticoid Receptor Assay Kit, Red (ThermoFisher A 15... |
US Patent US10668167 (2020)
BindingDB Entry DOI: 10.7270/Q2B56NSW |
More data for this
Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM445038
(US10668167, Compound 48)Show SMILES C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Cc2ccc(O)c(N)c2)cc1 |r,c:13,t:9| Show InChI InChI=1S/C35H39NO7/c1-33-12-11-23(38)15-22(33)8-9-24-25-16-30-35(29(41)18-37,34(25,2)17-28(40)31(24)33)43-32(42-30)21-6-3-19(4-7-21)13-20-5-10-27(39)26(36)14-20/h3-7,10-12,14-15,24-25,28,30-32,37,39-40H,8-9,13,16-18,36H2,1-2H3/t24-,25-,28-,30+,31+,32+,33-,34-,35+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.
US Patent
| Assay Description
Small molecules were tested for progersterone receptor (PR) binding using a modification of the LanthaScreen® TR-FRET Progesterone Receptor Coactivat... |
US Patent US10668167 (2020)
BindingDB Entry DOI: 10.7270/Q2B56NSW |
More data for this
Ligand-Target Pair | |
Estrogen receptor
(Homo sapiens (Human)) | BDBM445038
(US10668167, Compound 48)Show SMILES C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@H]1O[C@H](O[C@@]21C(=O)CO)c1ccc(Cc2ccc(O)c(N)c2)cc1 |r,c:13,t:9| Show InChI InChI=1S/C35H39NO7/c1-33-12-11-23(38)15-22(33)8-9-24-25-16-30-35(29(41)18-37,34(25,2)17-28(40)31(24)33)43-32(42-30)21-6-3-19(4-7-21)13-20-5-10-27(39)26(36)14-20/h3-7,10-12,14-15,24-25,28,30-32,37,39-40H,8-9,13,16-18,36H2,1-2H3/t24-,25-,28-,30+,31+,32+,33-,34-,35+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.
US Patent
| Assay Description
Small molecules were tested for estrogen receptor (ER) alpha binding using a modification of the LanthaScreen® TR-FRET Estrogen Receptor Alpha Coacti... |
US Patent US10668167 (2020)
BindingDB Entry DOI: 10.7270/Q2B56NSW |
More data for this
Ligand-Target Pair | |